Searchable abstracts of presentations at key conferences in endocrinology

ea0056p1148 | Thyroid cancer | ECE2018

Prediabetes and type 2 diabetes mellitus and risk of thyroid cancer

Grimmichova Tereza , Matucha Petr

Background: Increasing incidence of thyroid cancer may be attributable to sensitive diagnostic tools as well as changes in exposure to certain environmental factors. Type 2 diabetes mellitus (DM) reaches high prevalence worldwide. DM is a risk factor for many chronic disorders including cardiovascular disease and cancer. Insulin resistance (IR) is a fundamental aspect of the etiology of DM and compensatory hyperinsulinemia could promote cancer growth. The association between D...

ea0049ep1143 | Female Reproduction | ECE2017

Physiological changes of adipokines and selected steroids during the menstrual cycle

Šramkova Monika , Duškova Michaela , Vitků Jana , Včelak Josef , Matucha Petr , Bradnova Olga , Cordeiro Jose , Starka Luboslav

Context: The cyclical effects of hormones during the menstrual cycle (MC) are responsible for driving ovulation. The information about roles of adipokines within the scope of MC are not definite. Leptin plays a role in sexual function and regulating the onset of puberty. Thin girls often fail to ovulate or release an egg from an ovary during menstruation cycles. Leptin also acts on specific receptors in the hypothalamus to inhibit appetite. Levels of leptin are increased in wo...